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A chimeric Sindbis-based vaccine protects cynomolgus macaques against a lethal aerosol challenge of eastern equine encephalitis virus

Eastern equine encephalitis virus (EEEV) is a mosquito-borne alphavirus that causes sporadic, often fatal disease outbreaks in humans and equids, and is also a biological threat agent. Two chimeric vaccine candidates were constructed using a cDNA clone with a Sindbis virus (SINV) backbone and struct...

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Bibliografske podrobnosti
Main Authors: Roy, Chad J., Adams, A. Paige, Wang, Eryu, Leal, Grace, Seymour, Robert L., Sivasubramani, Satheesh K., Mega, William, Frolov, Ilya, Didier, Peter J., Weaver, Scott C.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581708/
https://ncbi.nlm.nih.gov/pubmed/23333212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2013.01.014
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