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Photodegradation and Stabilization of Betamethasone-17 Valerate in Aqueous/Organic Solvents and Topical Formulations

The effects of solvent [acetonitrile, methanol, and acetonitrile/water mixture (20:80, v/v)], buffer concentration (phosphate buffer, pH 7.5), ionic strength and commonly employed adjuvants on the photodegradation of betamethasone-17 valerate in cream and gel formulations have been studied on exposu...

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Autors principals: Khattak, Saif-ur-Rehman, Shaikh, Dilnawaz, Ahmad, Iqbal, Usmanghani, Khan, Sheraz, Muhammad Ali, Ahmed, Sofia
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581653/
https://ncbi.nlm.nih.gov/pubmed/23250710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-012-9902-4
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