Development of rapid and highly sensitive HSPA1A promoter-driven luciferase reporter system for assessing oxidative stress associated with low-dose photodynamic therapy

Photodynamic therapy (PDT) is a regulatory-approved modality for treating a variety of malignant tumors. It induces tumor tissue damage via photosensitizer-mediated oxidative cytotoxicity. The heat shock protein 70 (HSP70-1) is a stress protein encoded by the HSPA1A gene and is significantly induced...

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Autors principals: Zheng, Yuanhong, Le, Vanminh, Cheng, Zhuoan, Xie, Sheng, Li, Hegeng, Tian, Jianhui, Liu, Jianwen
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2012
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581624/
https://ncbi.nlm.nih.gov/pubmed/23160804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-012-0374-y
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