Autophagy and Cellular Senescence Mediated by Sox2 Suppress Malignancy of Cancer Cells

Autophagy is a critical cellular process required for maintaining cellular homeostasis in health and disease states, but the molecular mechanisms and impact of autophagy on cancer is not fully understood. Here, we found that Sox2, a key transcription factor in the regulation of the “stemness” of emb...

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Autori principali: Cho, Yong-Yeon, Kim, Dong Joon, Lee, Hye Suk, Jeong, Chul-Ho, Cho, Eun-Jin, Kim, Myong-Ok, Byun, Sanguine, Lee, Kun-Yeong, Yao, Ke, Carper, Andria, Langfald, Alyssa, Bode, Ann M., Dong, Zigang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581442/
https://ncbi.nlm.nih.gov/pubmed/23451179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057172
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