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Mammalian Complex I Pumps 4 Protons per 2 Electrons at High and Physiological Proton Motive Force in Living Cells

Mitochondrial complex I couples electron transfer between matrix NADH and inner-membrane ubiquinone to the pumping of protons against a proton motive force. The accepted proton pumping stoichiometry was 4 protons per 2 electrons transferred (4H(+)/2e(−)) but it has been suggested that stoichiometry...

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Bibliographic Details
Main Authors: Ripple, Maureen O., Kim, Namjoon, Springett, Roger
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581419/
https://ncbi.nlm.nih.gov/pubmed/23306206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.438945
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