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Gene Replacement Strategies to Test the Functional Redundancy of Basic Helix–Loop–Helix Transcription Factor

Basic helix–loop–helix (bHLH) transcription factors control developmental decisions for a wide range of embryonic cell types. Hand1 and Hand2 are closely related bHLH proteins that control cardiac, craniofacial, and limb development. Within the developing heart, Hand1 expression becomes restricted p...

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Bibliographic Details
Main Authors: Firulli, Anthony B., Firulli, Beth A., Wang, Jian, Rogers, Rhonda H., Conway, Simon J.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581321/
https://ncbi.nlm.nih.gov/pubmed/20155416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00246-010-9669-x
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