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Gene therapy using IL-27 ameliorates Sjögren's syndrome-like autoimmune exocrinopathy

INTRODUCTION: Sjögren's syndrome (SjS) is a systemic autoimmune disease characterized by decreased salivary and lacrimal gland secretions, resulting in severe dry mouth and dry eyes. Recent studies have suggested that T(H)17 cells and its signature cytokine IL-17 are involved in the underlying...

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Detalhes bibliográficos
Main Authors: Lee, Byung Ha, Carcamo, Wendy C, Chiorini, John A, Peck, Ammon B, Nguyen, Cuong Q
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580566/
https://ncbi.nlm.nih.gov/pubmed/22827855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3925
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