Polymorphisms in cytochrome P450 2C19 enzyme and cessation of leflunomide in patients with rheumatoid arthritis

INTRODUCTION: Rational selection of disease modifying anti-rheumatic drugs in the treatment of rheumatoid arthritis (RA) has many potential advantages, including rapid disease control, reduced long-term disability and reduced overall cost to the healthcare system. Inter-individual genetic difference...

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Autores principales: Wiese, Michael D, Schnabl, Matthew, O'Doherty, Catherine, Spargo, Llewellyn D, Sorich, Michael J, Cleland, Leslie G, Proudman, Susanna M
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580556/
https://ncbi.nlm.nih.gov/pubmed/22784880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3911
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