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Beta-lactamase inhibitors from laboratory to clinic.

beta-Lactamases constitute the major defense mechanism of pathogenic bacteria against beta-lactam antibiotics. When the beta-lactam ring of this antibiotic class is hydrolyzed, antimicrobial activity is destroyed. Although beta-lactamases have been identified with clinical failures for over 40 years...

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Bibliografske podrobnosti
izdano v:Clin Microbiol Rev
Glavni avtor: Bush, K
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1988
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358033/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3060240/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/cmr.1.1.109
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