Vinculin Regulates the Recruitment and Release of Core Focal Adhesion Proteins in a Force-Dependent Manner

BACKGROUND: Cells sense the extracellular environment using adhesion receptors (integrins) linked to the intracellular actin cytoskeleton through a complex network of regulatory proteins that, all together, form focal adhesions (FAs). The molecular basis of how these sensing units are regulated, how...

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Hauptverfasser: Carisey, Alex, Tsang, Ricky, Greiner, Alexandra M., Nijenhuis, Nadja, Heath, Nikki, Nazgiewicz, Alicja, Kemkemer, Ralf, Derby, Brian, Spatz, Joachim, Ballestrem, Christoph
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580286/
https://ncbi.nlm.nih.gov/pubmed/23375895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2013.01.009
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