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Wiskott-Aldrich Syndrome at the nexus of autoimmune and primary immunodeficiency diseases
Wiskott-Aldrich Syndrome (WAS) is a X-linked primary immunodeficiency disorder also marked by a very high (up to 70%) incidence of autoimmunity. Wiskott-Aldrich Syndrome arises from mutations in the Wiskott-Aldrich Syndrome protein (WASp), a cytoplasmic protein that links signaling by cell surface r...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3580218/ https://ncbi.nlm.nih.gov/pubmed/22036785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2011.10.031 |
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