Topical TLR7 agonist imiquimod can induce immune-mediated rejection of skin metastases in patients with breast cancer

PURPOSE: Skin metastases of breast cancer remain a therapeutic challenge. Toll-like receptor 7 agonist imiquimod is an immune response modifier and can induce immune-mediated rejection of primary skin malignancies when topically applied. Here we tested the hypothesis that topical imiquimod stimulate...

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Autores principales: Adams, Sylvia, Kozhaya, Lina, Martiniuk, Frank, Meng, Tze-Chiang, Chiriboga, Luis, Liebes, Leonard, Hochman, Tsivia, Shuman, Nicholas, Axelrod, Deborah, Speyer, James, Novik, Yelena, Tiersten, Amy, Goldberg, Judith D., Formenti, Silvia, Bhardwaj, Nina, Unutmaz, Derya, Demaria, Sandra
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580198/
https://ncbi.nlm.nih.gov/pubmed/22767669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-1149
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