Antineoplastic Effects of α-Santalol on Estrogen Receptor-Positive and Estrogen Receptor-Negative Breast Cancer Cells through Cell Cycle Arrest at G2/M Phase and Induction of Apoptosis

Anticancer efficacy and the mechanism of action of α-santalol, a terpenoid isolated from sandalwood oil, were investigated in human breast cancer cells by using p53 wild-type MCF-7 cells as a model for estrogen receptor(ER)-positive and p53 mutated MDA-MB-231 cells as a model for ER-negative breast...

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Detalhes bibliográficos
Main Authors: Santha, Sreevidya, Bommareddy, Ajay, Rule, Brittny, Guillermo, Ruth, Kaushik, Radhey S., Young, Alan, Dwivedi, Chandradhar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579946/
https://ncbi.nlm.nih.gov/pubmed/23451128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056982
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