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Increased Adiposity, Dysregulated Glucose Metabolism and Systemic Inflammation in Galectin-3 KO Mice

Obesity and type 2 diabetes are associated with increased production of Galectin-3 (Gal-3), a protein that modulates inflammation and clearance of glucose adducts. We used Lean and Diet-induced Obese (DIO) WT and Gal-3 KO mice to investigate the role of Gal-3 in modulation of adiposity, glucose meta...

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Détails bibliographiques
Auteurs principaux: Pang, Jingbo, Rhodes, Davina H., Pini, Maria, Akasheh, Rand T., Castellanos, Karla J., Cabay, Robert J., Cooper, Dianne, Perretti, Mauro, Fantuzzi, Giamila
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579848/
https://ncbi.nlm.nih.gov/pubmed/23451284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057915
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