Vitamin and antioxidant rich diet increases MLH1 promoter DNA methylation in DMT2 subjects

BACKGROUND: Oxidative stress may lead to an increased level of unrepaired cellular DNA damage, which is discussed as one risk for tumor initiation. Mismatch repair (MMR) enzymes act as proofreading complexes that maintain the genomic integrity and MMR-deficient cells show an increased mutation rate....

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Switzeny, Olivier J, Müllner, Elisabeth, Wagner, Karl-Heinz, Brath, Helmut, Aumüller, Eva, Haslberger, Alexander G
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579724/
https://ncbi.nlm.nih.gov/pubmed/23025454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-4-19
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