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Steerable-filter based quantification of axonal populations at the developing optic chiasm reveal significant defects in Slit2(−/−) as well as Slit1(−/−)Slit2(−/−) embryos

BACKGROUND: Previous studies have suggested that the axon guidance proteins Slit1 and Slit2 co-operate to establish the optic chiasm in its correct position at the ventral diencephalic midline. This is based on the observation that, although both Slit1 and Slit2 are expressed around the ventral midl...

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Détails bibliographiques
Auteurs principaux: Down, Matthew, Willshaw, David A, Pratt, Thomas, Price, David J
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579723/
https://ncbi.nlm.nih.gov/pubmed/23320558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-14-9
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