Comprehensive Search for Alzheimer Disease Susceptibility Loci in the APOE Region

OBJECTIVE: To evaluate the association of risk and age at onset (AAO) of Alzheimer disease (AD) with single-nucleotide polymorphisms (SNPs) in the chromosome 19 region including apolipoprotein E (APOE) and a repeat-length polymorphism in TOMM40 (poly-T, rs10524523). DESIGN: Conditional logistic regr...

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Autores principales: Jun, Gyungah, Vardarajan, Badri N., Buros, Jacqueline, Yu, Chang-En, Hawk, Michele V., Dombroski, Beth A., Crane, Paul K., Larson, Eric B., Mayeux, Richard, Haines, Jonathan L., Lunetta, Kathryn L., Pericak-Vance, Margaret A., Schellenberg, Gerard D., Farrer, Lindsay A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579659/
https://ncbi.nlm.nih.gov/pubmed/22869155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneurol.2012.2052
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