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Sonic Hedgehog Initiates Cochlear Hair Cell Regeneration through Downregulation of Retinoblastoma Protein

Cell cycle re-entry by cochlear supporting cells and/or hair cells is considered one of the best approaches for restoring hearing loss as a result of hair cell damage. To identify mechanisms that can be modulated to initiate cell cycle re-entry and hair cell regeneration, we studied the effect of ac...

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Autors principals: Lu, Na, Chen, Yan, Wang, Zhengmin, Chen, Guoling, Lin, Qin, Chen, Zheng-Yi, Li, Huawei
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579567/
https://ncbi.nlm.nih.gov/pubmed/23211596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.11.088
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