Enhanced Effect of Human Cardiac Stem Cells and Bone Marrow Mesenchymal Stem Cells to Reduce Infarct Size and Restore Cardiac Function after Myocardial Infarction

BACKGROUND: As mesenchymal stem cells (MSCs) induce proliferation and differentiation of c-kit+ cardiac stem cells (CSCs) in vivo and in vitro, we hypothesized that combining human (h)MSCs with c-kit+ hCSCs produces greater infarct size reduction compared to either cell administered alone after MI....

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Detalhes bibliográficos
Main Authors: Williams, Adam R., Hatzistergos, Konstantinos E., Addicott, Benjamin, McCall, Fred, Carvalho, Decio, Suncion, Viky, Morales, Azorides R., Silva, Jose Da, Sussman, Mark A., Heldman, Alan W., Hare, Joshua M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579523/
https://ncbi.nlm.nih.gov/pubmed/23224061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.112.131110
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