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Rapid Chemically Induced Changes of PtdIns(4,5)P(2) Gate KCNQ Ion Channels

To resolve the controversy about messengers regulating KCNQ ion channels during phospholipase C–mediated suppression of current, we designed translocatable enzymes that quickly alter the phosphoinositide composition of the plasma membrane after application of a chemical cue. The KCNQ current falls r...

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Bibliografische gegevens
Hoofdauteurs: Suh, Byung-Chang, Inoue, Takanari, Meyer, Tobias, Hille, Bertil
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579521/
https://ncbi.nlm.nih.gov/pubmed/16990515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1131163
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