Malignant Peripheral Nerve Sheath Tumor Invasion Requires Aberrantly Expressed Epidermal Growth Factor (EGF) Receptors and is Variably Enhanced by Multiple EGF Family Ligands

Aberrant epidermal growth factor receptor (EGFR) expression promotes the pathogenesis of malignant peripheral nerve sheath tumors (MPNSTs), the most common malignancy associated with neurofibromatosis type 1, but the mechanisms by which EGFR expression promotes MPNST pathogenesis are poorly understo...

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Hlavní autoři: Byer, Stephanie J., Brossier, Nicole M., Peavler, Lafe T., Eckert, Jenell M., Watkins, Stacey, Roth, Kevin A., Carroll, Steven L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579504/
https://ncbi.nlm.nih.gov/pubmed/23399900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e3182859939
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