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Gene Expression Profiles Can Predict Panitumumab Monotherapy Responsiveness in Human Tumor Xenograft Models

BACKGROUND: Epidermal growth factor receptor (EGFR)-targeted agents have demonstrated clinical benefit in patients with cancer. Identifying tissue-of-origin-independent predictive biomarkers is important to optimally treat patients. We sought to identify a gene array profile that could predict respo...

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Bibliografski detalji
Glavni autori: Boedigheimer, Michael J, Freeman, Daniel J, Kiaei, Panteha, Damore, Michael A, Radinsky, Robert
Format: Artigo
Jezik:Inglês
Izdano: Neoplasia Press Inc. 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579315/
https://ncbi.nlm.nih.gov/pubmed/23441127
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