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Pharmacogenomics of warfarin in populations of African descent

Warfarin is the most commonly prescribed oral anticoagulant worldwide despite its narrow therapeutic index and the notorious inter- and intra-individual variability in dose required for the target clinical effect. Pharmacogenetic polymorphisms are major determinants of warfarin pharmacokinetic and d...

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Bibliografske podrobnosti
Main Authors: Suarez-Kurtz, Guilherme, Botton, Mariana R
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579249/
https://ncbi.nlm.nih.gov/pubmed/22676711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2012.04354.x
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