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The Structure of Myristoylated Mason-Pfizer Monkey Virus Matrix Protein and the Role of Phosphatidylinositol-(4,5)-Bisphosphate in Its Membrane Binding

We determined the solution structure of myristoylated Mason-Pfizer monkey virus matrix protein by NMR spectroscopy. The myristoyl group is buried inside the protein and causes a slight reorientation of the helices. This reorientation leads to the creation of a binding site for phosphatidylinositols....

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Detalhes bibliográficos
Main Authors: Prchal, Jan, Srb, Pavel, Hunter, Eric, Ruml, Tomáš, Hrabal, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579217/
https://ncbi.nlm.nih.gov/pubmed/22863803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.07.021
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