A Small Molecule (Pluripotin) as a Tool for Studying Cancer Stem Cell Biology: Proof of Concept

BACKGROUND: Cancer stem cells (CSC) are thought to be responsible for tumor maintenance and heterogeneity. Bona fide CSC purified from tumor biopsies are limited in supply and this hampers study of CSC biology. Furthermore, purified stem-like CSC subpopulations from existing tumor lines are unstable...

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Bibliografische gegevens
Hoofdauteurs: Mertins, Susan D., Scudiero, Dominic A., Hollingshead, Melinda G., Divelbiss, Raymond D., Alley, Michael C., Monks, Anne, Covell, David G., Hite, Karen M., Salomon, David S., Niederhuber, John E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578829/
https://ncbi.nlm.nih.gov/pubmed/23437320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057099
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