A Small Molecule (Pluripotin) as a Tool for Studying Cancer Stem Cell Biology: Proof of Concept

BACKGROUND: Cancer stem cells (CSC) are thought to be responsible for tumor maintenance and heterogeneity. Bona fide CSC purified from tumor biopsies are limited in supply and this hampers study of CSC biology. Furthermore, purified stem-like CSC subpopulations from existing tumor lines are unstable...

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Detalhes bibliográficos
Main Authors: Mertins, Susan D., Scudiero, Dominic A., Hollingshead, Melinda G., Divelbiss, Raymond D., Alley, Michael C., Monks, Anne, Covell, David G., Hite, Karen M., Salomon, David S., Niederhuber, John E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578829/
https://ncbi.nlm.nih.gov/pubmed/23437320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057099
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