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Increased Levels of Survivin, via Association With Heat Shock Protein 90, in Mucosal T Cells From Patients With Crohn’s Disease

BACKGROUND & AIMS: Defective apoptosis of lamina propria T cells (LPTs) is involved in the pathogenesis of Crohn’s disease. Survivin, a member of the inhibitors of apoptosis family, prevents cell death and regulates cell division. Survivin has been studied extensively in cancer, but little is kn...

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Detalhes bibliográficos
Main Authors: DE SOUZA, HEITOR S. P., WEST, GAIL A., REBERT, NANCY, DE LA MOTTE, CAROL, DRAZBA, JUDY, FIOCCHI, CLAUDIO
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578578/
https://ncbi.nlm.nih.gov/pubmed/22749932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2012.06.039
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