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Nanofiber-mediated inhibition of focal adhesion kinase sensitizes glioma stemlike cells to epidermal growth factor receptor inhibition

BACKGROUND: Glioblastoma multiforme is the most common glioma in adults and carries a poor prognosis, due to tumor recurrence despite aggressive treatment. Such relapse has been attributed to the persistence of glioma stemlike cells (GSCs), a subpopulation of glioma cells with stem cell properties....

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Detalhes bibliográficos
Main Authors: Srikanth, Maya, Das, Sunit, Berns, Eric J., Kim, Juno, Stupp, Samuel I., Kessler, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578490/
https://ncbi.nlm.nih.gov/pubmed/23328812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos316
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