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First Generation Stochastic Gene Episilencing (Step1) Model and Applications to in Vitro Carcinogen Exposure

A novel first-generation stochastic gene episilencing (STEP1) model is introduced for quantitatively characterizing the probability of in vitro epigenetically silencing (episilencing) specific tumor-suppressor-microRNA (miRNA) genes by carcinogen exposure. Although the focus is mainly on in-vitro ex...

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Главный автор: Scott, Bobby R.
Формат: Artigo
Язык:Inglês
Опубликовано: International Hormesis Society 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578451/
https://ncbi.nlm.nih.gov/pubmed/23550217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2203/dose-response.11-007.Scott
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