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C-MYC Controlled TIP110 Protein Expression Regulates OCT4 mRNA Splicing in Human Embryonic Stem Cells

We reported previously that HIV-1 the Tat-interacting protein of 110 kDa (TIP110; P110(NRB)/SART3/p110) is important in regulation of hematopoiesis, and in maintaining pluripotent factor (NANOG, OCT4, and SOX2) expression in and pluripotency of human embryonic stem cells (hESCs). Here we show that T...

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Bibliographische Detailangaben
Hauptverfasser: Liu, Ying, Timani, Khalid, Ou, Xuan, Broxmeyer, Hal E., He, Johnny J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578368/
https://ncbi.nlm.nih.gov/pubmed/23088399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2012.0271
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