Donor killer immunoglobulin-like receptor genes and reactivation of cytomegalovirus after HLA-matched hematopoietic stem-cell transplantation: HLA-C allotype is an essential cofactor

Natural killer (NK) cells whose killer immunoglobulin-like receptors (KIRs) recognize human leukocyte antigen (HLA) ligand are “licensed” for activity. In contrast, non-licensed NK cells display KIRs for which ligand is absent from the self genotype and are usually hyporesponsive. Surprisingly, non-...

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Hlavní autoři: Behrendt, Carolyn E., Nakamura, Ryotaro, Forman, Stephen J., Zaia, John A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2013
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578282/
https://ncbi.nlm.nih.gov/pubmed/23440333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00036
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