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CD8α(+) DC trans-presentation of IL-15 to naïve CD8(+) T cells produces antigen inexperienced T cells in the periphery with memory phenotype and function

Various populations of memory phenotype CD8(+) T cells have been described over the last 15–20 years, all of which possess elevated effector functions relative to naïve phenotype cells. Using a technique for isolating antigen specific cells from unprimed hosts, we recently identified a new subset of...

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Main Authors: Sosinowski, Tomasz, White, Jason T., Cross, Eric, Haluszczak, Catherine, Marrack, Philippa, Gapin, Laurent, Kedl, Ross M.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578102/
https://ncbi.nlm.nih.gov/pubmed/23355737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203149
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