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Protein Tyrosine Nitration: Biochemical Mechanisms and Structural Basis of its Functional Effects
The nitration of protein tyrosine residues to 3-nitrotyrosine represents an oxidative postranslational modification that unveils the disruption of nitric oxide (•NO) signaling and metabolism towards pro-oxidant processes. Indeed, excess levels of reactive oxygen species in the presence of (•)NO or (...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3577981/ https://ncbi.nlm.nih.gov/pubmed/23157446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ar300234c |
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