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Protein Tyrosine Nitration: Biochemical Mechanisms and Structural Basis of its Functional Effects

The nitration of protein tyrosine residues to 3-nitrotyrosine represents an oxidative postranslational modification that unveils the disruption of nitric oxide (•NO) signaling and metabolism towards pro-oxidant processes. Indeed, excess levels of reactive oxygen species in the presence of (•)NO or (...

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Détails bibliographiques
Auteur principal: Radi, Rafael
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577981/
https://ncbi.nlm.nih.gov/pubmed/23157446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ar300234c
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