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Polycomb Domain Formation Depends on Short and Long Distance Regulatory Cues

BACKGROUND: Polycomb group (PcG) proteins dynamically define cellular identities through the epigenetic repression of key developmental genes. In Drosophila, cis-regulatory regions termed PcG response elements (PREs) act as nucleation sites for PcG proteins to create large repressive PcG domains tha...

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Bibliographic Details
Main Authors: Schuettengruber, Bernd, Cavalli, Giacomo
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577894/
https://ncbi.nlm.nih.gov/pubmed/23437158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056531
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