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Leishmania major Methionine Sulfoxide Reductase A Is Required for Resistance to Oxidative Stress and Efficient Replication in Macrophages

Leishmania are protozoan parasites that proliferate within the phagolysome of mammalian macrophages. While a number of anti-oxidant systems in these parasites have been shown to protect against endogenous as well as host-generated reactive oxygen species, the potential role of enzymes involved in th...

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Detalhes bibliográficos
Main Authors: Sansom, Fiona M., Tang, Leonie, Ralton, Julie E., Saunders, Eleanor C., Naderer, Thomas, McConville, Malcolm J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577802/
https://ncbi.nlm.nih.gov/pubmed/23437085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056064
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