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A Novel Domain Regulating Degradation of the Glomerular Slit Diaphragm Protein Podocin in Cell Culture Systems

Mutations in the gene NPHS2 are the most common cause of hereditary steroid-resistant nephrotic syndrome. Its gene product, the stomatin family member protein podocin represents a core component of the slit diaphragm, a unique structure that bridges the space between adjacent podocyte foot processes...

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Autors principals: Gödel, Markus, Ostendorf, Benjamin N., Baumer, Jessica, Weber, Katrin, Huber, Tobias B.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577791/
https://ncbi.nlm.nih.gov/pubmed/23437316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057078
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