12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase

The purpose of the current study was to evaluate the effect of 12/15- lipoxygenase (12/15-LOX) metabolites on retinal endothelial cell (REC) barrier function. FITC-dextran flux across the REC monolayers and electrical cell-substrate impedance sensing (ECIS) were used to evaluate the effect of 12- an...

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Main Authors: Othman, Amira, Ahmad, Saif, Megyerdi, Sylvia, Mussell, Rene, Choksi, Karishma, Maddipati, Krishna Rao, Elmarakby, Ahmed, Rizk, Nasser, Al-Shabrawey, Mohamed
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577708/
https://ncbi.nlm.nih.gov/pubmed/23437353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057254
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