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Reverse myocardial effects of intermedin in pressure-overloaded hearts: role of endothelial nitric oxide synthase activity

Intermedin (IMD) is a cardiac peptide synthesized in a prepro form, which undergoes a series of proteolytic cleavages and amidations to yield the active forms of 47 (IMD(1−47)) and 40 amino acids (IMD(8−47)). There are several lines of evidence of increased IMD expression in rat models of cardiac pa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pires, Ana Luísa, Pinho, Marta, Alves, Bárbara Silvana, Pinho, Sónia, Sena, Cristina, Seica, Raquel Maria, Leite-Moreira, Adelino F
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577549/
https://ncbi.nlm.nih.gov/pubmed/23165766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.240812
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