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Hypoxia–reoxygenation-induced endothelial barrier failure: role of RhoA, Rac1 and myosin light chain kinase
Hypoxia–reoxygenation induces loss of endothelial barrier function and oedema formation, which presents a major impediment for recovery of the organ. The integrity of the endothelial barrier is highly dependent on its contractile machinery and actin dynamics, which are precisely regulated by Rho GTP...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3577518/ https://ncbi.nlm.nih.gov/pubmed/23090948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.237834 |
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