Curcumin derivatives promote Schwann cell differentiation and improve neuropathy in R98C CMT1B mice

Charcot–Marie–Tooth disease type 1B is caused by mutations in myelin protein zero. R98C mice, an authentic model of early onset Charcot–Marie–Tooth disease type 1B, develop neuropathy in part because the misfolded mutant myelin protein zero is retained in the endoplasmic reticulum where it activates...

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Detalhes bibliográficos
Main Authors: Patzkó, Ágnes, Bai, Yunhong, Saporta, Mario A., Katona, István, Wu, XingYao, Vizzuso, Domenica, Feltri, M. Laura, Wang, Suola, Dillon, Lisa M., Kamholz, John, Kirschner, Daniel, Sarkar, Fazlul H., Wrabetz, Lawrence, Shy, Michael E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577101/
https://ncbi.nlm.nih.gov/pubmed/23250879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aws299
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