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Neoadjuvant cetuximab, twice-weekly gemcitabine, and intensity-modulated radiotherapy (IMRT) in patients with pancreatic adenocarcinoma

BACKGROUND: Neoadjuvant therapy has been investigated for localized and locally advanced pancreatic ductal adenocarcinoma (PDAC) but no standard of care exists. Combination cetuximab/gemcitabine/radiotherapy demonstrates encouraging preclinical activity in PDAC. We investigated cetuximab with twice-...

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Main Authors: Pipas, J. M., Zaki, B. I., McGowan, M. M., Tsapakos, M. J., Ripple, G. H., Suriawinata, A. A., Tsongalis, G. J., Colacchio, T. A., Gordon, S. R., Sutton, J. E., Srivastava, A., Smith, K. D., Gardner, T. B., Korc, M., Davis, T. H., Preis, M., Tarczewski, S. M., MacKenzie, T. A., Barth, R. J.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577039/
https://ncbi.nlm.nih.gov/pubmed/22571859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mds109
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