Diurnal sedative changes during intensive care: impact on liberation from mechanical ventilation and delirium

OBJECTIVE: To determine whether benzodiazepine and propofol doses are increased at night and whether daytime and nighttime sedative doses are associated with delirium, coma, and delayed liberation from mechanical ventilation. DESIGN: Single-center, prospective cohort study nested within the Awakenin...

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Main Authors: Seymour, Christopher W., Pandharipande, Pratik P., Koestner, Tyler, Hudson, Leonard D., Thompson, Jennifer L., Shintani, Ayumi K., Ely, E. Wesley, Girard, Timothy D.
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576216/
https://ncbi.nlm.nih.gov/pubmed/22824928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e31825b8ade
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