Enhanced oral absorption of 20(S)-protopanaxadiol by self-assembled liquid crystalline nanoparticles containing piperine: in vitro and in vivo studies

BACKGROUND: 20(S)-protopanaxadiol (PPD), similar to several other anticancer agents, has low oral absorption and is extensively metabolized. These factors limit the use of PPD for treatment of human diseases. METHODS: In this study, we used cubic nanoparticles containing piperine to improve the oral...

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Detalhes bibliográficos
Main Authors: Jin, Xin, Zhang, Zhen-hai, Sun, E, Tan, Xiao-bin, Li, Song-lin, Cheng, Xu-dong, You, Ming, Jia, Xiao-bin
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576041/
https://ncbi.nlm.nih.gov/pubmed/23426652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S38203
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