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Expression of Human CAR Splicing Variants in BAC-Transgenic Mice
The nuclear receptor constitutive androstane receptor (CAR) is a key regulator for drug metabolism in liver. Human CAR (hCAR) transcripts are subjected to alternative splicing. Some hCAR splicing variants (SVs) have been shown to encode functional proteins by reporter assays. However, in vivo resear...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3576005/ https://ncbi.nlm.nih.gov/pubmed/23152187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs321 |
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