Blockade of VEGFR-1 and VEGFR-2 Enhances Paclitaxel Sensitivity in Gastric Cancer Cells

PURPOSE: Hypoxia-inducible factor-1α (HIF-1α) increases transcription of the vascular endothelial growth factor (VEGF) gene. Inhibition of VEGF abolishes VEGF mediated induction of HIF-1α. Recent reports suggested that HIF-1α also mediated the induction of class III β-tubulin (TUBB3) in hypoxia. TUB...

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Hlavní autoři: Hwang, Jun-Eul, Lee, Ji-Hee, Park, Mi-Ra, Kim, Dae-Eun, Bae, Woo-Kyun, Shim, Hyun-Jeong, Cho, Sang-Hee, Chung, Ik-Joo
Médium: Artigo
Jazyk:Inglês
Vydáno: Yonsei University College of Medicine 2013
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575962/
https://ncbi.nlm.nih.gov/pubmed/23364970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3349/ymj.2013.54.2.374
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