Imprinting at the PLAGL1 domain is contained within a 70-kb CTCF/cohesin-mediated non-allelic chromatin loop

Paternal duplications of chromosome 6q24, a region that contains the imprinted PLAGL1 and HYMAI transcripts, are associated with transient neonatal diabetes mellitus. A common feature of imprinted genes is that they tend to cluster together, presumably as a result of sharing common cis-acting regula...

Full description

Saved in:
Bibliographic Details
Main Authors: Iglesias-Platas, Isabel, Court, Franck, Camprubi, Cristina, Sparago, Angela, Guillaumet-Adkins, Amy, Martin-Trujillo, Alex, Riccio, Andrea, Moore, Gudrun E., Monk, David
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
Subjects:
Gene Regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575839/
https://ncbi.nlm.nih.gov/pubmed/23295672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1355
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items