Structures of apo- and ssDNA-bound YdbC from Lactococcus lactis uncover the function of protein domain family DUF2128 and expand the single-stranded DNA-binding domain proteome

Single-stranded DNA (ssDNA) binding proteins are important in basal metabolic pathways for gene transcription, recombination, DNA repair and replication in all domains of life. Their main cellular role is to stabilize melted duplex DNA and protect genomic DNA from degradation. We have uncovered the...

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Main Authors: Rossi, Paolo, Barbieri, Christopher M., Aramini, James M., Bini, Elisabetta, Lee, Hsiau-Wei, Janjua, Haleema, Xiao, Rong, Acton, Thomas B., Montelione, Gaetano T.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
Structural Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575825/
https://ncbi.nlm.nih.gov/pubmed/23303792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1348
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