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Synthetic gene expression perturbation systems with rapid, tunable, single-gene specificity in yeast
A general method for the dynamic control of single gene expression in eukaryotes, with no off-target effects, is a long-sought tool for molecular and systems biologists. We engineered two artificial transcription factors (ATFs) that contain Cys(2)His(2) zinc-finger DNA-binding domains of either the...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3575806/ https://ncbi.nlm.nih.gov/pubmed/23275543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1313 |
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