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Evidence that a consensus element found in naturally intronless mRNAs promotes mRNA export

We previously showed that mRNAs synthesized from three genes that naturally lack introns contain a portion of their coding sequence, known as a cytoplasmic accumulation region (CAR), which is essential for stable accumulation of the intronless mRNAs in the cytoplasm. The CAR in each mRNA is unexpect...

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Hlavní autoři: Lei, Haixin, Zhai, Bo, Yin, Shanye, Gygi, Steve, Reed, Robin
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
RNA
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575797/
https://ncbi.nlm.nih.gov/pubmed/23275560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1314
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