In Vitro Engineering of Vascularized Tissue Surrogates

In vitro scaling up of bioengineered tissues is known to be limited by diffusion issues, specifically a lack of vasculature. Here, we report a new strategy for preserving cell viability in three-dimensional tissues using cell sheet technology and a perfusion bioreactor having collagen-based microcha...

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Main Authors: Sakaguchi, Katsuhisa, Shimizu, Tatsuya, Horaguchi, Shigeto, Sekine, Hidekazu, Yamato, Masayuki, Umezu, Mitsuo, Okano, Teruo
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575583/
https://ncbi.nlm.nih.gov/pubmed/23419835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01316
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