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CD8 T Cell Memory Recall Is Enhanced by Novel Direct Interactions with CD4 T Cells Enabled by MHC Class II Transferred from APCs

Protection against many intracellular pathogens is provided by CD8 T cells, which are thought to need CD4 T cell help to develop into effective memory CD8 T cells. Because murine CD8 T cells do not transcribe MHC class II (MHC-II) genes, several models have proposed antigen presenting cells (APCs) a...

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Main Authors: Romagnoli, Pablo A., Premenko-Lanier, Mary F., Loria, Gilbert D., Altman, John D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575485/
https://ncbi.nlm.nih.gov/pubmed/23441229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056999
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